Technologies
AGC supports a wide range of custom manufacturing projects.
- Fine Chemicals
- Electronic Materials
- Agrochemical Intermediates
- Agrochemical Active Ingredients
- Pharmaceutical Intermediates
- Active Pharmaceutical Ingredients (APIs)
Achieving High Reproducibility, High Quality, and Reliable Supply in Contract Manufacturing Based on an Extensive Track Record
- A proven track record trusted by more than 110 companies across a wide range of industries
- Expanded production capacity through continued investment
- Resolution of all scale-up challenges from pilot production to commercial manufacturing
AGC's Synthetic Track Record at a Glance
One-Stop Support for All Manufacturing Scales with One of the Largest Reactor Capacities in Japan
Leveraging extensive experience and one of the largest manufacturing facilities in Japan, AGC supports customers in bringing their products to commercialization. To meet demands across all manufacturing scales—from pilot production to large-scale manufacturing—we are equipped with reactors ranging from 100 L to 15,000 L. By applying know-how cultivated through high-performance chemicals such as electronic materials, functional materials, and various intermediates, we provide a one-stop optimal production system tailored to each customer's business plan, covering everything from development to commercial-scale production.

Up to 1,000 kg per batch
Supported Production Scales
We provide a flexible, one-stop production system optimized to align with each customer's business plan.
As of October 2025
Scale-Up Track Record
Experienced engineers support smooth technology transfer from laboratory to commercial production. By resolving challenges in process development, we contribute to maximizing the value of our customers' products.
Continuously supplied (As of Oct. 2025)
Number of products in continuous supply
We continue to be selected by many customers in highly specialized fields such as high-performance chemicals, electronic materials, agrochemicals, and pharmaceuticals. With a proven track record of delivering the required quality reliably and on schedule, we contribute to our customers' business success.
2008–2025
Quality Deviation Lot Rate
Under a rigorous quality control system, we maintain an exceptionally low rate of quality deviations, delivering industry-leading quality standards.
In-house sourced
Ratio of Raw Materials with Multiple Sourcing
For major raw materials, we collaborate with multiple suppliers to prepare for unforeseen events. From a business continuity planning (BCP) perspective, we have established an uninterrupted supply system.
As of October 2025
Number of Customers Under Contract Manufacturing / Under Consideration
Our extensive expertise and know-how are our key assets. Leveraging this experience, we gain a clear understanding of project-specific challenges, enabling smooth and efficient project execution with minimal rework.
Cumulative Manufacturing and Development Track Record in Contract Synthesis: Over 700 Companies
To date, we have supported manufacturing and development projects for more than 700 companies. Each experience gained from meeting diverse customer needs has become a valuable asset. Going forward, we will continue to leverage our accumulated technologies and expertise to contribute to solving our customers' challenges.
List of Available Reactions
AGC is a leading chemical manufacturer equipped with world-class organic synthesis technologies, production technologies, and manufacturing facilities.
We have extensive experience in the manufacturing and handling of halogenated compounds and are capable of working with all four halogens: fluorine (F), chlorine (Cl), bromine (Br), and iodine (I).
Leveraging our extensive experience in a wide range of organic synthesis, including low-temperature and hydrogenation reactions, we effectively meet our customers' diverse needs.
Bond Forming Reactions
- Enolate-Mediated Reactions
- Amination
- Radical Addition
- Radical Halogenation
- Chain Extension and Shortening (Decarboxylation)
- Amidation
Oxidation Reactions
- TEMPO Oxidation
- Hypochlorite Oxidation
- Periodate Oxidation
- Bromine Oxidation
Reduction Reactions
- LAH (Lithium Aluminum Hydride) Reduction
- Catalytic Hydrogenation
- Reductive Amination
- Metal Reduction (Fe, Zn)
- Silane Reduction
Aromatic Substitution
- Friedel-Crafts
- Halogenation
- Suzuki coupling
- Buchwald coupling
Hazardous Reactions
- Cyanation
- Fluorination (F₂ Gas, Chiba Site)
- Chlorination (Cl₂ Gas)
- Difluoromethylation
- Balz-Schiemann Reaction (Fluorination)
Specialized Equipment & Capabilities
- Precision Distillation (up to ~40 stages)
- Ultra-Low Temperature Reactions (down to ~−100°C)
- Pressurized Reactions (up to ~0.6 MPa)
- Milling / Pulverization
Fluorine & Halogen Chemistry
- Halogenation Reactions (F, Cl, Br, I)
- Halogen Exchange Reactions
- Synthesis of Fluorinated Heterocycles
- Introduction of Perfluoroalkyl Groups
- Advanced Corrosion-Resistant Facilities
- Iodine Recovery and Recycling
Various Organic Synthesis Technologies
- Amidation
- Corey–Chaykovsky Reaction
- Friedel–Crafts Reaction
- Grignard Reaction
- Various Cross-Coupling Reactions
- Carboxylation
- Oxidation
- Reduction (Hydrogenation)
- Reactions Using High-Pressure Gases (Toxic and Flammable)
- High-Temperature Reactions (up to ~250°C, jacket temperature)
- Low-Temperature Reactions (down to −50°C, jacket temperature)
- Distillation (Atmospheric and Reduced Pressure)
- Thin-Film Distillation
- Flow Reactions (Under Development)
- Photochemical Reactions (Under Development)
Available Raw Materials
Raw materials produced within the AGC Group.
CAS No. 76-05-1
Trifluoroacetic acid
CAS No. 407-25-0
Trifluoroacetic anhydride
CAS No. 383-63-1
Ethyl trifluoroacetate
CAS No. 2923-18-4
Sodium trifluoroacetate
CAS No. 354-38-1
Trifluoroacetamide
CAS No. 677-69-0
Heptafluoro-2-iodopropane
CAS No. 455-14-1
4-(trifluoromethyl)aniline
CAS No. 122665-97-8
4,4-difluorocyclohexane carboxylic acid
CAS No. 148043-73-6
4,4,5,5,5-Pentafluoro-1-pentanol
CAS No.30071-93-3
3,5-Bis(trifluoromethyl)acetophenone
CAS No. 3862-73-5
2,3,4-Trifluoroaniline
CAS No. 328-93-8
2,5-Bis(trifluoromethyl)aniline
CAS No. 214557-89-8
3,5,7-trifluoroadamantane carboxylic acid
CAS No. 118612-00-3
N,N-Dimethylanilinium tetrakis-(pentafluorophenyl)borate
CAS No. 136040-19-2
Triphenylcarbenium tetrakis-(pentafluorophenyl) borate
CAS No.75-29-6
2-chloropropane
CAS No. 557-98-2
2-chloropropene
CAS No. 542-75-6
1,3-dichloropropene
CAS No.96-18-4
1,2,3-trichloropropane
CAS No. 142-28-9
1,3-dichloropropane
CAS No. 96-24-2
3-chloro-1,2-propanediol
CAS No.96-23-1
1,3-dichloro-2-propanol
CAS No.627-30-5
3-chloro-1-propanol
CAS No. 616-30-8
3-amino-1,2-propanediol
CAS No.107-11-9
3-amino-1-propene
CAS No.124-02-7
diallylamine
CAS No. 102-70-5
triallylamine