Small-Molecule Pharmaceutical CDMO Services

About Our Small-Molecule Pharmaceutical CDMO Services

Over 40 years of track record and global presence ensuring stable supply of pharmaceutical APIs and intermediates

As both a CMO (Contract Manufacturing Organisation) and CDMO (Contract Development and Manufacturing Organisation), we have been providing contract development and manufacturing of pharmaceutical APIs and intermediates for over 40 years. We continue to deliver high-level GMP-compliant quality management and stable supply, supporting the manufacturing outsourcing needs of our customers.

Key Features of AGC Fine Chemicals' Small-Molecule Pharmaceutical CDMO

Global manufacturing network

We operate cGMP-compliant manufacturing sites in Japan (Chiba) and Europe (Spain), enabling us to meet global customer requirements.

Optimal process proposals using diverse equipment

Equipped with cryogenic reaction systems and reactors of various sizes (100 to 15,000 L), we can propose the most suitable process tailored to your specific requirements.

Outstanding fluorine chemistry expertise

From general organic chemistry reactions to fluorination and cryogenic reactions, we deliver superior quality in small-molecule pharmaceutical manufacturing.

Key Reactions

General organic reactions	Grignard, lithiation, cross-coupling, acetylation, Friedel–Crafts, oxidation/reduction reactions (TEMPO oxidation, hypochlorite oxidation, Vilsmeier, silane reduction), fluorination reactions (halogenation, nucleophilic fluorination)
Novel synthesis route development using fluorine-containing building blocks	(CCHF₂), various tetrafluoroethylene derivatives, fluorine-containing gases
Hazardous reactions	Cyanation, C₂H₂ gas
General carboxylic acid intermediate manufacturing	CO₂ insertion reaction under N₂ atmosphere

Supported Reactions

• Hydrogenation reactions
• Cryogenic reactions (down to −100°C)
• Distillation (under GMP)
• Highly potent API (HPAPI) manufacturing facilities

Enquiries & Technical Materials

We are happy to provide technical documentation upon request. Please feel free to contact us via our enquiry form.